I think small businesses are better than big ones. I think they're better for communities, better for individuals, better for a competitive market (which is the only remotely acceptable way to do capitalism) and better for the public purse.
That said, I also agree with this critique by Maia of Capitalism Bad, Tree Pretty.
It all comes down to this:
we can never trust the owners of business to act in the interests of anything but their bottom line, no matter how socially conscious they are, no matter how much they're part of our community, no matter how much they're providing a service we want.